Projects
From spiking neurons to brain waves
15 Oct 2008- 31 Mar 2013In this research project we will test three hypotheses. The first hypothesis is related to the functional role of neuronal oscillations in the gamma-f…
Microbial ecosystems and multiple environment stoichiometric analyses
1 Nov 2008- 1 Oct 2011The attainable flux states of a metabolic network of an organism result from selective pressures acting on the organism's ability to cope with: (i) ch…
Modeling gene networks in synaptic computation: A Bayesian pertubation approach
1 Nov 2008- 31 Oct 2012The synapse is the basic unit of computation in the brain. Its ability to adapt its strength on a millisecond timescale is a prerequisite for informat…
Multi-scale modelling of calcification in scleratinin corals
1 Jun 2009In most cases, form and structure of corals are determined on the micro-level ? the classical method. In this project, the research will focus on gene…
Neuronal Netwerk Formation through Reciprocal Interacties between Activity and Structure
1 Dec 2008- 12 Jan 2011Information processing in the brain is based on the dynamics of electrical activity in large neuronal networks. Activity dynamics depends on network s…
Reverse physiology of the cortical microcircuit
1 Jun 2009This project focuses on the way in which a single neuron (nerve cell) involves cells in its direct environment in distributing collected information. …
The co-evolution of the receptor signalling network of natural killer cells with its ligands
1 Jun 2009Natural killer cells play an important role in the immune system. These cells recognise infected cells using their external inhibiting and activating …
The evolution of stochastic heterogeneous networks as bet-hedging adaptations to fluctuating environments
1 Jun 2009In the single-celled organism Bacillus subtilis, the formation process of spores can adapt to extreme circumstances. However, even though all cells ar…
The regulatory network underlying malaria parasite-host interactions
1 Jun 2009In the life cycle of the malaria parasite, entering a red blood cell is a crucial step. The parasite can employ different mechanisms to enter, dependi…
Understanding hierarchical and metabolic regulation of metabolic networks through Bayesian constraint modelling
1 Dec 2008- 1 Dec 2012Integration of datasets for understanding the interplay between the various levels of cellular organization is an important aspect of today's (systems…