Programme April 25
Below you can find the preliminary conference programme for April 25th.
| 08:30 - 09:00 | Registration with coffee & tea |
| 09:00 - 09:05 | Opening by Marcel Reinders (scientific director NBIC) |
I) Keynote session - Europazaal (chair: Marcel Reinders)
| 09:05 - 09:50 | Keynote: Prof. Gerard J. Kleywegt, Protein Data Bank in Europe (PDBe), |
| EMBL-EBI, "Just because it's in Nature, doesn't mean it's true..." |
J) Parallel session: Networks - Amerika zaal (chair: Perry Moerland)
| 9:50 - 10:10 | Chris Oates, Netherlands Cancer Institute |
| Network Inference Using Chemical Kinetics | |
| 10:10 - 10:30 | Mohammed El-Kebir, VU University Amsterdam & CWI |
| NatalieWEB: A web server for topology-aware global protein-protein | |
| interaction network comparison |
K) Parallel session: Growth - Azie zaal (chair: Dick de Ridder)
| 9:50 - 10:10 | Philip Lijnzaad, Molecular Cancer Research, UMC Utrecht |
| Using Singular Value Decomposition to extricate population effects | |
| in perturbation studies of yeast. | |
| 10:10 - 10:30 | Aldert Zomer, Radboud UMC Nijmegen |
| Detection of genes essential for growth of respiratory pathogens |
L) Parallel session: Infrastructure & Support (DISC) - Zaal 5
| 09:50 - 10:03 | Irene Nooren, University of Amsterdam |
| e-BioGrid: Building a Dutch e-science infrastructure for life science research. | |
| 10:03 - 10:16 | Gera Pronk, SURFnet |
| NBIC as IDP - what does it mean for you? | |
| 10:16 - 10:30 | Jan Bot, Leiden University |
| BiG Grid infrastructure: Facilitating the computational needs for current | |
| bioinformatics applications |
M) NSBM Spring Meeting - Vide 1+2 (Chair: Gerry Nicolaes)
| 09:50 - 10:10 | Anton Feenstra, VU University Amsterdam |
| Fast and accurate calculation of protein-protein interaction: contribution | |
| of surface and interface residues | |
| 10:10 - 10:30 | Rob van der Kant, CMBI, UMC St Radboud Nijmegen |
| GPCR activation: What moves where? |
N) NL BioImaging AM Side Meeting - Zaal 3 (Chair: Dorus Gadella)
| 09:50 - 10:10 | Thomas Schmidt, Physics of Life Processes, Cell Observatory, |
| Leiden University | |
| Partitioning of HRas studied by super-resolution imaging. | |
| 10:10 - 10:30 | Mark Hink, van Leeuwenhoek Centre for Advanced Microscopy, SILS, |
| University of Amsterdam | |
| Quantitative live-cell microscopy using new developed fluorescent | |
| proteins in fluorescence fluctuation spectroscopy. | |
| 10:30 - 11:30 | Coffee & tea break |
| - Poster session (Even numbers) - Europazaal | |
| - Application showcase - Entrance hall | |
| - Market place |
O) Parallel session: Metabolism - Amerika zaal (chair: Hans van Beek)
| 11:30 - 11:50 | Konrad Zych, Groningen Bioinformatics Centre, University of Groningen |
| Computational analysis of the modular architecture of secondary | |
| metabolite biosynthesis gene clusters | |
| 11:50 - 12:10 | Hannes Hettling, VU University Amsterdam |
| Computational Estimation of Tricarboxylic Acid Cycle Fluxes | |
| in Heart from Noisy NMR Data |
P) Parallel session: Transcriptional Regulation - Azie zaal (chair: Bas Teusink)
| 11:30 - 11:50 | Christof Francke, Radboud UMC / TI Food & Nutrition |
| The use of comparative genomics to uncover the conserved biological | |
| role of transcription regulators | |
| 11:50 - 12:10 | Jose M Muino, Wageningen UR |
| Going beyond the CArG-box: Understanding the temperature dependent | |
| DNA binding of MADS-domain transcription factors |
Q) Parallel session: Infrastructure & Support (DISC) - Zaal 5
| 11:30 - 11:43 | Jildau Bouwman, TNO |
| Structured data analysis and storage to facilitate systems biology analysis. | |
| 11:43 - 11:56 | Eleni Mina, Leiden University Medical Center |
| e-Science in bioinformatics: enabling the reuse of methods while unravelling | |
| the epigenetic factors of Huntington's Disease. | |
| 11:56 - 12:10 | Egon Willighagen, Maastricht University |
| Contributions to the Chemistry Development Kit for metabolomics and drug | |
| discovery: twelve years of Dutch involvement in the Open Source | |
| cheminformatics library. |
R) NSBM Spring Meeting - Vide 1+2 (Chair: Gerry Nicolaes)
| 11:30 - 11:50 | Hein Wijma, University of Groningen |
| Combination of computational design and directed evolution as a | |
| strategy to dramatically stabilize enzymes | |
| 11:50 - 12:10 | Bastiaan van den Berg, Delft University of Technology |
| An enzyme redesign method for improved production rates in | |
| Aspergillus niger |
S) NL BioImaging AM Side Meeting - Zaal 3 (Chair: Dorus Gadella)
| 11:30-11:50 | Jack Fransen, Microscopic Imaging Centre, NCMLS, Radboud UMC |
| High-content microscopy of cytotoxic T –cell effector function in a | |
| migration-dependent organotypic culture assay. | |
| 11:50-12:10 | Daniël Lam, Department of Molecular Cell Biology, Sanquin Research. |
| SETting the stage: Image Analysis in Cell Biology. | |
| 12:10 - 13:50 | Lunch buffet |
| Market Place: BIUP meeting point, stands |
T) Parallel session: Regulation - Amerika zaal (chair: Berend Snel)
| 13:50 - 14:10 | Evert Bosdriesz, VU University Amsterdam |
| Optimal and robust regulation of gene expression | |
| 14:10 - 14:30 | Wilco Fleuren, CMBI/CDD, Radboud UMC, Nijmegen |
| Studying mechanisms of prednisolone induced metabolic side effects | |
| in adipose tissue. | |
| 14:30 - 14:50 | Marnix Medema, University of Groningen |
| Computational Genomics and Synthetic Biology Implementation of | |
| Microbial Secondary Metabolite Biosynthesis Pathways |
U) Parallel session: NGS variation detection - Azie zaal (chair: Kai Ye)
| 13:50 - 14:10 | Joep de Ligt, Radboud UMC, Nijmegen |
| Identification of novel Intellectual Disability genes through | |
| detection of de novo mutations | |
| 14:10 - 14:30 | Yanju Zhang, Leiden University Medical Center |
| PASSion: A Pattern Growth Algorithm Based Pipeline for Splice | |
| Junction Detection in Paired-end RNA-Seq Data | |
| 14:30 - 14:50 | Eric-Wubbo Lameijer, Leiden University Medical Center |
| Pindel 2: detecting insertions, deletions, inversions and tandem | |
| duplications in next-generation sequencing data |
V) NSBM Spring Meeting - Vide 1+2 (Chair: Gerry Nicolaes)
| 13:50 - 14:50 | Prof Gerard J. Kleywegt, Protein Data Bank in Europe (PDBe), |
| EMBL-EBI |
W) NL BioImaging AM Side Meeting - Zaal 3 (Chair: Dorus Gadella)
| 13:50-14:10 | Farzad Fereidouni, Department of Molecular Biophysics, Debye Institute, |
| Utrecht University | |
| Spectral phasor analysis allows rapid and reliable unmixing of | |
| fluorescence microscopy spectral images. | |
| 14:10-14:30 | Ulrike Schnell, Dept. of Cell Biology, University Medical Center Groningen |
| Immunolabeling artifacts and the need for live-cell imaging. | |
| 14:30-14:50 | Werner Koopman, Department of Biochemistry, NCMLS, Radboud UMC |
| Towards a system biological understanding of mitochondrial structure | |
| and function in health and disease. | |
| 14:50 - 15:50 | Coffee & Tea break |
| - Poster session (odd numbers) | |
| - Application showcase | |
| - Market Place |
X) Plenary session - Europazaal (chair Marcel Reinders)
| 15:50 - 16:20 | Lecture Jaap Heringa, Scientific Director NBIC |
| "BioWise: Wising up to bioinformatics education" | |
| 16:20 - 16:50 | Presentation of the NBIC Young Investigator Award 2012 |
Y) Keynote session - Europazaal
| 16:50 - 17:35 Keynote: Keynote: Dorus Gadella, SILS, University of Amsterdam. |
| The microscopy and bioimaging revolution: seeing is believing. |
Z) Plenary session - Europazaal (chair: Marcel Reinders)
| 17:35 - 18:05 | Award ceremony: |
| - NBIC Poster Award | |
| - BioWise Student Poster Prize | |
| - Application Showcase Award | |
| - Award for best lecture | |
| 18:05 | Closing of the conference |