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Programme April 25

Below you can find the preliminary conference programme for April 25th.

08:30 - 09:00 Registration with coffee & tea
09:00 - 09:05 Opening by Marcel Reinders (scientific director NBIC)

I) Keynote session - Europazaal (chair: Marcel Reinders)

09:05 - 09:50 Keynote: Prof. Gerard J. Kleywegt, Protein Data Bank in Europe (PDBe),
  EMBL-EBI, "Just because it's in Nature, doesn't mean it's true..."

J) Parallel session: Networks - Amerika zaal (chair: Perry Moerland)

9:50 - 10:10 Chris Oates, Netherlands Cancer Institute
  Network Inference Using Chemical Kinetics
10:10 - 10:30 Mohammed El-Kebir, VU University Amsterdam & CWI
  NatalieWEB: A web server for topology-aware global protein-protein
  interaction network comparison

K) Parallel session: Growth - Azie zaal (chair: Dick de Ridder)

9:50 - 10:10 Philip Lijnzaad, Molecular Cancer Research, UMC Utrecht
  Using Singular Value Decomposition to extricate population effects
  in perturbation studies of yeast.
10:10 - 10:30 Aldert Zomer, Radboud UMC Nijmegen
  Detection of genes essential for growth of respiratory pathogens

L) Parallel session: Infrastructure & Support (DISC) - Zaal 5

09:50 - 10:03 Irene Nooren, University of Amsterdam
  e-BioGrid: Building a Dutch e-science infrastructure for life science research.
10:03 - 10:16 Gera Pronk, SURFnet
  NBIC as IDP - what does it mean for you?
10:16 - 10:30 Jan Bot, Leiden University
  BiG Grid infrastructure: Facilitating the computational needs for current
  bioinformatics applications

M) NSBM Spring Meeting - Vide 1+2 (Chair: Gerry Nicolaes)

09:50 - 10:10 Anton Feenstra, VU University Amsterdam
  Fast and accurate calculation of protein-protein interaction: contribution
  of surface and interface residues
10:10 - 10:30 Rob van der Kant, CMBI, UMC St Radboud Nijmegen
  GPCR activation: What moves where?

N) NL BioImaging AM Side Meeting - Zaal 3 (Chair: Dorus Gadella)

09:50 - 10:10 Thomas Schmidt, Physics of Life Processes, Cell Observatory,
  Leiden University
  Partitioning of HRas studied by super-resolution imaging.
10:10 - 10:30 Mark Hink, van Leeuwenhoek Centre for Advanced Microscopy, SILS,
  University of Amsterdam
  Quantitative live-cell microscopy using new developed fluorescent
  proteins in fluorescence fluctuation spectroscopy.
10:30 - 11:30 Coffee & tea break
  - Poster session (Even numbers) - Europazaal
  - Application showcase - Entrance hall
  - Market place

O) Parallel session: Metabolism - Amerika zaal (chair: Hans van Beek)

11:30 - 11:50 Konrad Zych, Groningen Bioinformatics Centre, University of Groningen
  Computational analysis of the modular architecture of secondary
  metabolite biosynthesis gene clusters
11:50 - 12:10 Hannes Hettling, VU University Amsterdam
  Computational Estimation of Tricarboxylic Acid Cycle Fluxes
  in Heart from Noisy NMR Data

P) Parallel session: Transcriptional Regulation - Azie zaal (chair: Bas Teusink)

11:30 - 11:50 Christof Francke, Radboud UMC / TI Food & Nutrition
  The use of comparative genomics to uncover the conserved biological
  role of transcription regulators
11:50 - 12:10 Jose M Muino, Wageningen UR
  Going beyond the CArG-box: Understanding the temperature dependent
  DNA binding of MADS-domain transcription factors

Q) Parallel session: Infrastructure & Support (DISC) - Zaal 5

11:30 - 11:43 Jildau Bouwman, TNO
  Structured data analysis and storage to facilitate systems biology analysis.
11:43 - 11:56 Eleni Mina, Leiden University Medical Center
  e-Science in bioinformatics: enabling the reuse of methods while unravelling
  the epigenetic factors of Huntington's Disease.
11:56 - 12:10 Egon Willighagen, Maastricht University
  Contributions to the Chemistry Development Kit for metabolomics and drug
  discovery: twelve years of Dutch involvement in the Open Source
  cheminformatics library.

R) NSBM Spring Meeting - Vide 1+2 (Chair: Gerry Nicolaes)

11:30 - 11:50 Hein Wijma, University of Groningen
  Combination of computational design and directed evolution as a
  strategy to dramatically stabilize enzymes
11:50 - 12:10 Bastiaan van den Berg, Delft University of Technology
  An enzyme redesign method for improved production rates in
  Aspergillus niger

S) NL BioImaging AM Side Meeting - Zaal 3 (Chair: Dorus Gadella)

11:30-11:50 Jack Fransen, Microscopic Imaging Centre, NCMLS, Radboud UMC
  High-content microscopy of cytotoxic T –cell effector function in a
  migration-dependent organotypic culture assay.
11:50-12:10 Daniël Lam, Department of Molecular Cell Biology, Sanquin Research.
  SETting the stage: Image Analysis in Cell Biology.
12:10 - 13:50 Lunch buffet
  Market Place: BIUP meeting point, stands

T) Parallel session: Regulation - Amerika zaal (chair: Berend Snel)

13:50 - 14:10 Evert Bosdriesz, VU University Amsterdam
  Optimal and robust regulation of gene expression
14:10 - 14:30 Wilco Fleuren, CMBI/CDD, Radboud UMC, Nijmegen
  Studying mechanisms of prednisolone induced metabolic side effects
  in adipose tissue.
14:30 - 14:50 Marnix Medema, University of Groningen
  Computational Genomics and Synthetic Biology Implementation of
  Microbial Secondary Metabolite Biosynthesis Pathways

U) Parallel session: NGS variation detection - Azie zaal (chair: Kai Ye)

13:50 - 14:10 Joep de Ligt, Radboud UMC, Nijmegen
  Identification of novel Intellectual Disability genes through
  detection of de novo mutations
14:10 - 14:30 Yanju Zhang, Leiden University Medical Center
  PASSion: A Pattern Growth Algorithm Based Pipeline for Splice
  Junction Detection in Paired-end RNA-Seq Data
14:30 - 14:50 Eric-Wubbo Lameijer, Leiden University Medical Center
  Pindel 2: detecting insertions, deletions, inversions and tandem
  duplications in next-generation sequencing data

V) NSBM Spring Meeting - Vide 1+2 (Chair: Gerry Nicolaes)

13:50 - 14:50 Prof Gerard J. Kleywegt, Protein Data Bank in Europe (PDBe),

W) NL BioImaging AM Side Meeting - Zaal 3 (Chair: Dorus Gadella)

13:50-14:10 Farzad Fereidouni, Department of Molecular Biophysics, Debye Institute,
  Utrecht University
  Spectral phasor analysis allows rapid and reliable unmixing of
  fluorescence microscopy spectral images.
14:10-14:30 Ulrike Schnell, Dept. of Cell Biology, University Medical Center Groningen
  Immunolabeling artifacts and the need for live-cell imaging.
14:30-14:50 Werner Koopman, Department of Biochemistry, NCMLS, Radboud UMC
  Towards a system biological understanding of mitochondrial structure
  and function in health and disease.
14:50 - 15:50 Coffee & Tea break
  - Poster session (odd numbers)
  - Application showcase
  - Market Place

X) Plenary session - Europazaal (chair Marcel Reinders)

15:50 - 16:20 Lecture Jaap Heringa, Scientific Director NBIC
  "BioWise: Wising up to bioinformatics education"
16:20 - 16:50 Presentation of the NBIC Young Investigator Award 2012

Y) Keynote session - Europazaal

16:50 - 17:35 Keynote: Keynote: Dorus Gadella, SILS, University of Amsterdam.
The microscopy and bioimaging revolution: seeing is believing.

Z) Plenary session - Europazaal (chair: Marcel Reinders)

17:35 - 18:05 Award ceremony:
  - NBIC Poster Award
  - BioWise Student Poster Prize
  - Application Showcase Award
  - Award for best lecture
18:05 Closing of the conference